This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
GOAT ANTI HUMAN ABCB5
catalog :
MBS223834
quantity :
0.1 mg
price :
515 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
product information
catalog number :
MBS223834
products type :
Antibody
products full name :
GOAT ANTI HUMAN ABCB5
products short name :
ABCB5
other names :
ATP-binding cassette sub-family B member 5 isoform 1; ATP-binding cassette sub-family B member 5; ATP-binding cassette sub-family B member 5; ABCB5 P-gp; ATP-binding cassette protein; P-glycoprotein ABCB5; ATP-binding cassette, sub-family B (MDR/TAP), member 5; ABCB5 P-gp; P-glycoprotein ABCB5
products gene name :
ABCB5
other gene names :
ABCB5; ABCB5; ABCB5beta; EST422562; ABCB5alpha
uniprot entry name :
ABCB5_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Goat
sequence length :
1257
specificity :
This item specifically recognises human ABCB5 (ATP-binding cassette sub-family B member 5), a P-glycoprotein and member of the conserved ABC transporter family, which acts as an energy-dependent efflux transporter for rhodamine. ABCB5 is primarily expressed by skin progenitor cells and shown to act as a regulator of cell fusion and determinant of membrane potential. Studies have revealed the expression of ABCB5 in human malignant melanoma tumours, and in particular its association with CD133+ stem cell phenotype-expressing cells.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 0.5mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: This item detects a band of approximately 80kDa in A431cell lysates. ELISA: Maximum Dilution: 1/128000. Western Blotting: Minimum Dilution: 0.03; Maximum Dilution: 0.1ug/ml
other info1 :
Perservative Stabilisers: 0.02% Sodium Azide (NaN3). 0.5% Bovine Serum Albumin
other info2 :
Immunogen: Peptide sequence C-QTQHRNTSKKAQ from the internal region of ABCB5 (NP_848654.3). Buffer Solution: TRIS buffered saline. Antiserum Preparation: Antiserum to ABCB5 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human
products description :
MBS223834 specifically recognises human ABCB5 (ATP-binding cassette sub-family B member 5), a P-glycoprotein and member of the conserved ABC transporter family, which acts as an energy-dependent efflux transporter for rhodamine. ABCB5 is primarily expressed by skin progenitor cells and shown to act as a regulator of cell fusion and determinant of membrane potential. Studies have revealed the expression of ABCB5 in human malignant melanoma tumours, and in particular its association with CD133+ stem cell phenotype-expressing cells.
ncbi gi num :
255708477
ncbi acc num :
NP_001157413.1
ncbi gb acc num :
NM_001163941.1
uniprot acc num :
Q2M3G0
ncbi mol weight :
89,832 Da
ncbi pathways :
ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
size :
0.1 mg
price :
515 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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