product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Tyr-3/trp-5 Monooxygenase Activation Protein, Tau
catalog :
MBS143243
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143243
products type :
Recombinant Protein
products full name :
Recombinant Human Tyr-3/trp-5 Monooxygenase Activation Protein, Tau
products short name :
Tyr-3/trp-5 Monooxygenase Activation Protein
products name syn :
YWHAQ Human; Tyr-3/Trp- 5 Monooxygenase Activation Protein Theta Human Recombinant; 14-3-3 theta; 14-3-3 tau; 14-3-3 T-cell; HS1; YWHAQ; 1C5; 14-3-3 Tau; Tyr-3/Trp- 5 Monooxygenase Activation Protein Theta
other names :
14-3-3 protein theta; 14-3-3 protein theta; 14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
products gene name :
YWHAQ
other gene names :
YWHAQ; YWHAQ; 1C5; HS1; 14-3-3; N/A
uniprot entry name :
1433T_HUMAN
host :
E Coli
sequence length :
245
sequence :
MEKTELIQKA KLAEQAERYD DMATCMKAVT EQGAELSNEE RNLLSVAYKN VVGGRRSAWRVISSIEQKTD TSDKKLQLIK DYREKVESEL RSICTTVLEL LDKYLIANAT NPESKVFYLKMKGDYFRYLA EVACGDDRKQ TIDNSQGAYQ EAFDISKKEM QPTHPIRLGL ALNFSVFYYEILNNPELACT LAKTAFDEAI AELDTLNEDS YKDSTLIMQL LRDNLTLWTS DSAGEECDAA EGAEN.
purity :
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
YWHAQ solution containing 20mM Tris 7.5. Sterile filtered colorless solution.
storage stability :
YWHAQ Human Recombinant although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
products categories :
PROTEIN KINASES; Enzymes; 14-3-3
products description :
Description: YWHAQ Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 245 amino acids (1-245) and having a molecular mass of 27 kDa. YWHAQ is purified by proprietary chromatographic techniques. Introduction: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, ?, ?, ?, ?, ?, ? and ? that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis.
ncbi gi num :
5803227
ncbi acc num :
NP_006817.1
ncbi gb acc num :
NM_006826.3
uniprot acc num :
P27348
ncbi mol weight :
27,764 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Apoptosis Pathway 105648!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054!!Cell Cycle Pathway 463!!Class I PI3K Signaling Events Mediated By Akt Pathway 138020!!Epstein-Barr Virus Infection Pathway 585562
ncbi summary :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
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