This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-IDO1 / IDO Antibody (aa78-184, clone 10.1) LS-C45686
catalog :
LS-C45686
quantity :
100 µg
price :
755 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10.1
reactivity :
human
application :
western blot, immunohistochemistry - frozen section
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; human; 1:100; fig 2
Gulati N, Suárez-Fariñas M, Correa Da Rosa J, Krueger J. Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions. F1000Res. 2015;4:149 pubmed publisher
product information
AntibodyID :
45424
AntibodyName :
LS-C45686
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Anti-IDO1 / IDO Antibody (aa78-184, clone 10.1) LS-C45686
Specificity :
Recognizes Indoleamine-pyrrole 2,3 - dioxygenase (IDO), an enzyme responsible for the catabolism of tryptophan to N-formylkynurenine and kyneurenine. With the exception of tryptophan oxidase in hepatocytes, IDO is the only enzyme that degrades the amino acid tryptophan to kyneurenine. Chlamydial pathogens require tryptophan for growth. IDO can lower available tryptophan in target cells leading to conversion of the pathogen to persistent forms, with significance in the progression to chronic infection with its associated pathological effects.
ClonalityDesc :
Monoclonal
CloneName :
10.1
AntibodyModification :
Unconjugated
AntigenModification :
aa78-184
PresentationDesc :
PBS buffer with 0.1% NaN3 added as preservative
ImmunogenDesc :
Peptide corresponding to amino acids 78-184 of human IDO fused to GST.
PurificationDesc :
Purified
RecommendedStorageDesc :
+4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted.
IsotypeName :
IgG3
Gene :
IDO1 / IDO
StandardGeneSymbol :
IDO1
Reactivity :
Mouse, Human
Usage :
IHC-Fr, WB
UsageText :
Western Blot: LS-C45686 recognizes a 45kD band in IFN-gamma treated human cell lines. This antibody recognizes a slightly lower molecular weight band in Mouse IDO compared to its human counterpart.
Synonyms :
IDO1, IDO, Indole 2,3-dioxygenase, Indolamine 2,3 dioxygenase, IDO-1, INDO, Indoleamine 2,3-dioxygenase, Indoleamine 2,3-dioxygenase 1
ProductID :
54867
ProductNumber :
LS-C45686-100
Weight :
100 µg
Concentration :
1 mg/ml
LSListPrice :
755 USD
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.