product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-BACE1 / BACE Antibody (N-Terminus) IHC-plus™ LS-A8548
catalog :
LS-A8548
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
image
image 1 :
LifeSpan Biosciences LS-A8548 image 1
Human Brain, Alzheimers (formalin-fixed, paraffin-embedded) stained with BACE1 antibody LS-A8548 at 2.5-3 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.
product information
?AntibodyID :
3110
AntibodyName :
LS-A8548
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-BACE1 / BACE Antibody (N-Terminus) IHC-plus™ LS-A8548
Specificity :
Human BACE1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ZBTB47 (44%).
ClonalityDesc :
Polyclonal
AntigenModification :
N-Terminus
PresentationDesc :
PBS, less than 0.1% sodium azide.
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic 18 amino acid peptide from near N-terminus of human BACE1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rat (100%); Mouse, Bovine, Hamster, Panda (94%); Bat (89%); Elephant, Horse, Rabbit (83%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Long term: -70°C; Short term: +4°C
Gene :
BACE1 / BACE
StandardGeneSymbol :
BACE1
gene family :
Protease
Subfamily :
Aspartic A1
Reactivity :
Human, Monkey, Rat
Usage :
IHC-P (2.5 µg/ml)
UsageText :
Immunohistochemistry: LS-A8548 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A8548 was determined to be 2.5-3 ug/ml.
Synonyms :
BACE1, APP beta-secretase, Asp 2, ASP2, Aspartyl protease 2, Aspartylprotease 2, Beta-secretase, Beta-site APP-cleaving enzyme, BACE, HSPC104, KIAA1149, B-Secretase, Beta-secretase 1, Memapsin-2
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.