c-Met Polyclonal Antibody | Invitrogen 71-8000 product information

product summary

company name :

Invitrogen

other brands :

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product type :

antibody

product name :

c-Met Polyclonal Antibody

catalog :

71-8000

quantity :

100µg

price :

US 309.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, other

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
other; human; 1:800; fig s3 immunohistochemistry - paraffin section; human; 1:200; fig s4 immunocytochemistry; human; 1:1000; fig s2 western blot; human; 1:1000; fig s1	De Herdt M, Willems S, van der Steen B, Noorlag R, Verhoef E, van Leenders G, et al. Absent and abundant MET immunoreactivity is associated with poor prognosis of patients with oral and oropharyngeal squamous cell carcinoma. Oncotarget. 2016;7:13167-81 pubmed publisher
western blot; human; fig 4	Matte I, Lane D, Laplante C, Garde-Granger P, Rancourt C, Piche A. Ovarian cancer ascites enhance the migration of patient-derived peritoneal mesothelial cells via cMet pathway through HGF-dependent and -independent mechanisms. Int J Cancer. 2015;137:289-98 pubmed publisher
immunohistochemistry; human; 2 ug/ml; fig 4	McKay B, Toth K, Tarnopolsky M, Parise G. Satellite cell number and cell cycle kinetics in response to acute myotrauma in humans: immunohistochemistry versus flow cytometry. J Physiol. 2010;588:3307-20 pubmed publisher
immunocytochemistry; mouse; 1:200	Bernet J, Doles J, Hall J, Kelly Tanaka K, Carter T, Olwin B. p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice. Nat Med. 2014;20:265-71 pubmed publisher
immunohistochemistry - paraffin section; human; fig 4	Linton K, Hey Y, Saunders E, Jeziorska M, Denton J, Wilson C, et al. Acquisition of biologically relevant gene expression data by Affymetrix microarray analysis of archival formalin-fixed paraffin-embedded tumours. Br J Cancer. 2008;98:1403-14 pubmed publisher
	Saghizadeh M, Kramerov A, Yu F, Castro M, Ljubimov A. Normalization of wound healing and diabetic markers in organ cultured human diabetic corneas by adenoviral delivery of c-Met gene. Invest Ophthalmol Vis Sci. 2010;51:1970-80 pubmed publisher
	Takeuchi H, Bilchik A, Saha S, Turner R, Wiese D, Tanaka M, et al. c-MET expression level in primary colon cancer: a predictor of tumor invasion and lymph node metastases. Clin Cancer Res. 2003;9:1480-8 pubmed

product information

Product Type :

Antibody

Product Name :

c-Met Polyclonal Antibody

Catalog # :

71-8000

Quantity :

100µg

Price :

US 309.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: Assay Dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: Assay Dependent

Species :

Human

Isotype :

IgG

Storage :

-20°C

Description :

The c-Met oncogene was originally isolated from a chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a trans-membrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. The c-Met gene product has been identified as the cell surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration.

Immunogen :

Synthetic peptide derived from the C-terminal or the human c-Met protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: Assay Dependent

Aliases :

EC 2.7.10.1, HGF receptor, HGF-SF receptor, Hepatocyte growth factor receptor precursor, Met proto- oncogene tyrosine kinase, c-met, kinase EC 2.7.10.1, HGF receptor, HGF-SF receptor, Hepatocyte growth factor receptor precursor, Met proto- oncogene tyros

PubMed References :

12684423, 18382428, 19933191, 20624792, 24531379, 25482018, 26909606

more info or order :

Invitrogen product webpage