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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-IKK alpha (Ser176, Ser180) Polyclonal Antibody
catalog :
44-714
quantity :
10 blots
price :
US 309.00
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human
application :
western blot, immunocytochemistry
more info or order :
Invitrogen product webpage
product information
Product Type :
Antibody
Product Name :
Phospho-IKK alpha (Ser176, Ser180) Polyclonal Antibody
Catalog # :
44-714
Quantity :
10 blots
Price :
US 309.00
Clonality :
Polyclonal
Purity :
purified
Host :
Rabbit
Reactivity :
Human
Applications :
ChIP assay: 10µl, Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: 1:250
Species :
Human
Isotype :
IgG
Storage :
-80°C
Description :
Nuclear factor kappa B (NF-kappa-B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa-B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF-a and bacteria product LPS. NF-kappa-B is associated with Ikappa-B proteins in the cell cytoplasm, which inhibit NF-kappa-B activity. The long-sought Ikappa-B kinase (IKK), which phosphorylates Ikappa-B, and mediates Ikappa-B degradation and NF-kappa-B activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK-a and IKK-b). IKK-a and IKK-b interact with each other and both are essential for the NF-kappa-B activation. IKK-a specifically phosphorylates Ikappa-B-alpha. IKK-a is expressed in a variety of human tissues.
Immunogen :
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human IKK-alpha that contains serine 176 and serine 180.
Format :
Liquid
Applications w/Dilutions :
ChIP assay: 10µl, Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: 1:250
Aliases :
FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, IKBKB, IKK-B, IKK-beta, IKK2, IKKB, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, Inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, Nuclear facto
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
www.thermofisher.com
800-678-5599
headquarters: USA