Phospho-SMAD3 (Ser423, Ser425) Polyclonal Antibody | Invitrogen 44-246G product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-SMAD3 (Ser423, Ser425) Polyclonal Antibody

catalog :

44-246G

quantity :

10 blots

price :

US 309.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 7b	Zhu Y, Takayama T, Wang B, Kent A, Zhang M, Binder B, et al. Restenosis Inhibition and Re-differentiation of TGF?/Smad3-activated Smooth Muscle Cells by Resveratrol. Sci Rep. 2017;7:41916 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:400; fig 6	Tian X, Halfhill A, Diaz F. Localization of phosphorylated SMAD proteins in granulosa cells, oocytes and oviduct of female mice. Gene Expr Patterns. 2010;10:105-12 pubmed publisher
	Chai Z, Dai A, Tu Y, Li J, Wu T, Wang Y, et al. Genetic deletion of cell division autoantigen 1 retards diabetes-associated renal injury. J Am Soc Nephrol. 2013;24:1782-92 pubmed publisher
	Li H, Sekine M, Seng S, Avraham S, Avraham H. BRCA1 interacts with Smad3 and regulates Smad3-mediated TGF-beta signaling during oxidative stress responses. PLoS ONE. 2009;4:e7091 pubmed publisher
	Fujita N, Fujita S, Okada Y, Fujita K, Kitano A, Yamanaka O, et al. Impaired angiogenic response in the corneas of mice lacking osteopontin. Invest Ophthalmol Vis Sci. 2010;51:790-4 pubmed publisher
	de Guise C, Lacerte A, Rafiei S, Reynaud R, Roy M, Brue T, et al. Activin inhibits the human Pit-1 gene promoter through the p38 kinase pathway in a Smad-independent manner. Endocrinology. 2006;147:4351-62 pubmed

product information

Product Type :

Antibody

Product Name :

Phospho-SMAD3 (Ser423, Ser425) Polyclonal Antibody

Catalog # :

44-246G

Quantity :

10 blots

Price :

US 309.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: Assay Dependent

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20°C

Description :

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Immunogen :

The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human Smad3 that contains serine 423 and serine 425. This sequence is conserved in mouse.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: Assay Dependent

Aliases :

JV15-2, MAD-3, MADH3, Mad3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMAD 3, Smad 3

more info or order :

Invitrogen product webpage