RUNX2 Monoclonal Antibody (ZR002) | Invitrogen 41-1400 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RUNX2 Monoclonal Antibody (ZR002)

catalog :

41-1400

quantity :

100µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ZR002

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:400; fig 2f ELISA; human; 1:200; loading ...; tbl 2	Srikanth L, Sunitha M, Kumar P, Chandrasekhar C, Vengamma B, Sarma P. Gel based in vitro 3D model exploring the osteocytic potentiality of human CD34⁺ stem cells. Mol Biol Rep. 2016;43:1233-1242 pubmed
blocking or activating experiments; human; 1 ug/mL	Pilia M, Guda T, Shiels S, Appleford M. Influence of substrate curvature on osteoblast orientation and extracellular matrix deposition. J Biol Eng. 2013;7:23 pubmed publisher
	Baniwal S, Little G, Chimge N, Frenkel B. Runx2 controls a feed-forward loop between androgen and prolactin-induced protein (PIP) in stimulating T47D cell proliferation. J Cell Physiol. 2012;227:2276-82 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RUNX2 Monoclonal Antibody (ZR002)

Catalog # :

41-1400

Quantity :

100µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay Dependent, Western Blot: Assay Dependent

Species :

Human

Clone :

ZR002

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).

Immunogen :

Synthetic peptide derived from the C-terminal region of the human and mouse Runx2 proteins

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Western Blot: Assay Dependent

Aliases :

Runt-related transcription factor 2, Core-binding factor subunit alpha-1, CBF-alpha-1, Acute myeloid leukemia 3 protein, Oncogene AML-3, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit, Osteoblast-specific transcription factor 2, OSF-2, RUNX2, AML3, CBFA1, OSF2, PEBP2A

PubMed References :

21809344, 24090183, 27497820

more info or order :

Invitrogen product webpage