Cullin 5 Monoclonal Antibody (ZC009) | Invitrogen 39-9000 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cullin 5 Monoclonal Antibody (ZC009)

catalog :

39-9000

quantity :

100µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ZC009

reactivity :

human, mouse, rat

application :

western blot, ELISA

more info or order :

Invitrogen product webpage

citations: 1

Reference
Levy D, Rodríguez Buño R, Hu T, Moran A. The potential effects of tobacco control in China: projections from the China SimSmoke simulation model. BMJ. 2014;348:g1134 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cullin 5 Monoclonal Antibody (ZC009)

Catalog # :

39-9000

Quantity :

100µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: Assay Dependent, Western Blot: 1-2 µg/mL

Species :

Human, Mouse, Rat

Clone :

ZC009

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

Immunogen :

Synthetic peptide derived from the N-terminal region of the mouse and rat CUL-5/VACM-1 proteins, which are 89% homologous to human

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Western Blot: 1-2 µg/mL

Aliases :

VACM-1, VACM1, CUL-5, Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1), Vasopressin-activated calcium-mobilizing receptor-1, cullin-5, vasopressin-activated calcium-mobilizing receptor 1

more info or order :

Invitrogen product webpage