H-Ras Monoclonal Antibody (Y13-259) | Invitrogen 33-7200 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

H-Ras Monoclonal Antibody (Y13-259)

catalog :

33-7200

quantity :

50µg

price :

US 249.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

Y13-259

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, other

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
other; mouse; loading ...; fig 2a	Riecken L, Zoch A, Wiehl U, Reichert S, Scholl I, Cui Y, et al. CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins. Oncotarget. 2016;7:78242-78254 pubmed publisher
immunoprecipitation; mouse; fig 4	Tian W, Boss G, Cohen D. Ras signaling in the inner medullary cell response to urea and NaCl. Am J Physiol Cell Physiol. 2000;278:C372-80 pubmed
	Gapuzan M, Schmah O, Pollock A, Hoffmann A, Gilmore T. Immortalized fibroblasts from NF-kappaB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor alpha after transformation by v-Ras. Oncogene. 2005;24:6574-83 pubmed
	Hodgson L, Henderson A, Dong C. Melanoma cell migration to type IV collagen requires activation of NF-kappaB. Oncogene. 2003;22:98-108 pubmed

product information

Product Type :

Antibody

Product Name :

H-Ras Monoclonal Antibody (Y13-259)

Catalog # :

33-7200

Quantity :

50µg

Price :

US 249.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human, Mouse, Rat

Applications :

Immunofluorescence: Assay Dependent, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Species :

Human, Mouse, Rat

Clone :

Y13-259

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. These proteins function in signal transduction pathways. They can bind GTP and GDP, and they have intrinsic GTPase activity. HRAS undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in the HRAS gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma.

Immunogen :

Recombinant p21 ras protein.

Format :

Liquid

Applications w/Dilutions :

Immunofluorescence: Assay Dependent, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Aliases :

Ha-Ras, Harvey-ras, Hras, H-Ras-1, Transforming protein p21, c-H-ras, p21ras, Ras, GTPase Hras, Hras1

PubMed References :

10666033, 12527912, 16027734, 27793041

more info or order :

Invitrogen product webpage