Synuclein alpha/beta Monoclonal Antibody (Syn 202) | Invitrogen 32-8200 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Synuclein alpha/beta Monoclonal Antibody (Syn 202)

catalog :

32-8200

quantity :

100µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Syn 202

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 1

Reference
Cabin D, Shimazu K, Murphy D, Cole N, Gottschalk W, McIlwain K, et al. Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein. J Neurosci. 2002;22:8797-807 pubmed

product information

Product Type :

Antibody

Product Name :

Synuclein alpha/beta Monoclonal Antibody (Syn 202)

Catalog # :

32-8200

Quantity :

100µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: Assay Dependent, Immunocytochemistry: 1-2 ug/ml, Immunofluorescence: 1-2 ug/ml, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1-3 ug/ml

Species :

Human, Mouse, Rat

Clone :

Syn 202

Isotype :

IgG2a

Storage :

-20°C

Description :

Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.

Immunogen :

Recombinant human alpha- and beta-synuclein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Immunocytochemistry: 1-2 ug/ml, Immunofluorescence: 1-2 ug/ml, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1-3 ug/ml

Aliases :

Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, PARK1, PARK4, PD1, alpha-synuclein, non A-beta component of AD amyloid, synuclein alpha-140, SNCA, SNCB, alpha-synuclein, beta-synuclein

PubMed References :

12388586

more info or order :

Invitrogen product webpage