product summary
request information :
company name :
GeneTex
product type :
antibody
product name :
Estrogen Receptor alpha antibody [1F3]
catalog :
GTX70171
quantity :
100.00μg
price :
299 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
western blot, immunoprecipitation, FACS, immunohistochemistry - frozen section
more info or order :
citations: 3
Srilatha B, Adaikan P. Estrogen and phytoestrogen predispose to erectile dysfunction: do ER-alpha and ER-beta in the cavernosum play a role?. Urology. 2004;63:382-6 pubmed
Ivanova M, Mazhawidza W, Dougherty S, Minna J, Klinge C. Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells. Mol Cell Endocrinol. 2009;305:12-21 pubmed publisher
Sun M, Estrov Z, Ji Y, Coombes K, Harris D, Kurzrock R. Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol Cancer Ther. 2008;7:464-73 pubmed publisher
image
image 1 :
GeneTex GTX70171 image 1
Sample (30 ug of whole cell lysate) A: MCF7 7.5% SDS PAGE GTX70171 diluted at 1:500
product information
Catalog No :
GTX70171
Product Name :
Estrogen Receptor alpha antibody [1F3]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
100.00μg
List Price :
299 USD
list of Pubmed id :
19433257,18347134,14972507
Clone :
1F3
Isotype :
IgG1
Product Description :
Mouse Monoclonal antibody [1F3] to Estrogen Receptor alpha
CrossReactivity :
Hu, Rb
Background :
The Estrogen Receptor (ER) is a 65a protein and a member of the steroid family of nuclear receptors. ER is a ligand-activated transcription factor and, when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) sequences. When bound to DNA, ER can positively or negatively regulate gene transcription through the recruitment of coactivator (e.g. SRC-1) or corepressor (e.g. NCoR) proteins.
Immunogen :
The region encoding amino acids 1-190 expressed in E. coli.
Buffer :
Phosphate-buffered saline, pH 7.4, containing no preservatives
Uses :
FACS, IHC-Fr, IP, WB
Concentration :
2.61mg/ml
General References :
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
more info or order :
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
www.genetex.com
1-877-436-3839
headquarters: USA