product summary
request information :
company name :
GeneTex
product type :
antibody
product name :
Estrogen Receptor alpha antibody [1F3]
catalog :
GTX70171
quantity :
100 μg
price :
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
western blot, FACS, immunoprecipitation
publications citing this reagent :
  1. Ivanova M, Mazhawidza W, Dougherty S, Minna J, Klinge C. Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells. Mol Cell Endocrinol. 2009;305:12-21 PMID 19433257 CrossRef
  2. Sun M, Estrov Z, Ji Y, Coombes K, Harris D, Kurzrock R. Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol Cancer Ther. 2008;7:464-73 PMID 18347134 CrossRef
more info or order :
product information
CatNo :
GTX70171
Product Name :
Estrogen Receptor alpha antibody [1F3]
Host :
Mouse
TestedApplication :
FACS, IP, WB
OfficalName :
ER alpha
Fullname :
estrogen receptor 1
Synonyms :
P03372, ESR, major ORF, Era, ER, 133430, ER alpha, DKFZp686N23123, ESRA, NR3A1
ProductDescription :
Mouse monoclonal [1F3] to Estrogen Receptor alpha
Background :
The Estrogen Receptor (ER) is a 65a protein and a member of the steroid family of nuclear receptors. ER is a ligand-activated transcription factor and, when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) sequences. When bound to DNA, ER can positively or negatively regulate gene transcription through the recruitment of coactivator (e.g. SRC-1) or corepressor (e.g. NCoR) proteins.
Immunogen :
The region encoding amino acids 1-190 expressed in E. coli.
Clonality :
Monoclonal
Isotype :
IgG1
TargetName :
ER alpha
AntigenSpecies :
Human
ImmunogenRegion :
The region encoding amino acids 1-190 expressed in E. coli.
CalculatedMW :
65
PositiveControls :
MCF7
AppliactionNote :
For IP: Use at a concentration of 1-5 µg/ml. For WB: Use at a concentration of 1-5 µg/ml. Predicted molecular weight: 68 kDa. Not tested in other applications. Optimal dilutions/concentations should be determined by the researcher.
Reactivity :
Human
PackageUnit :
100 μg
Purification :
Protein G Affinity Purified
Buffer :
Phosphate-buffered saline, pH 7.4, containing no preservatives
StorageInstruction :
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
CellularLocalization :
Nuclear
PurificationNote :
From hybridoma tissue culture supernatant
more info or order :
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
www.genetex.com
1-877-436-3839
headquarters: USA