DNA ligase III antibody [6G9] | GeneTex GTX70147 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

DNA ligase III antibody [6G9]

catalog :

GTX70147

quantity :

100.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

clone name :

6G9

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

citations: 4

Published Application/Species/Dilution	Reference
	Vogel K, Perez M, Momand J, Acevedo-Torres K, Hildreth K, Garcia R, et al. Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice. Mol Reprod Dev. 2011;78:906-19 pubmed publisher
	Wang H, Rosidi B, Perrault R, Wang M, Zhang L, Windhofer F, et al. DNA ligase III as a candidate component of backup pathways of nonhomologous end joining. Cancer Res. 2005;65:4020-30 pubmed
	Lan L, Nakajima S, Oohata Y, Takao M, Okano S, Masutani M, et al. In situ analysis of repair processes for oxidative DNA damage in mammalian cells. Proc Natl Acad Sci U S A. 2004;101:13738-43 pubmed
	Allen D, Herbert D, McMahan C, Rotrekl V, Sobol R, Wilson S, et al. Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice. Biol Reprod. 2008;79:824-31 pubmed publisher

product information

Catalog No :

GTX70147

Product Name :

DNA ligase III antibody [6G9]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

299 USD

list of Pubmed id :

21919107,15365186,18650495,15899791

Clone :

6G9

Isotype :

IgG1

Product Description :

Mouse monoclonal [6G9] to DNA ligase III

CrossReactivity :

Hu, Ms

Background :

There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97kDa (§-form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.

Immunogen :

Recombinant full-length human DNA Ligase III-b.

Buffer :

Phosphate-buffered saline, pH 7.2, containing no preservativs

Uses :

ICC/IF, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.