product summary
request information :
company name :
GeneTex
product type :
antibody
product name :
p21 antibody [EPR3993]
catalog :
GTX62525
quantity :
100 μl
price :
clonality :
monoclonal
host :
rabbit
reactivity :
human, rat
application :
immunohistochemistry - paraffin section, western blot, immunoprecipitation
more info or order :
product information
CatNo :
GTX62525
Product Name :
p21 antibody [EPR3993]
Host :
Rabbit
TestedApplication :
IHC-P, IP, WB
OfficalName :
CDKN1A
Fullname :
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Synonyms :
CDKN1A, P21, MDA-6, SDI1, MDA6, p21CIP1, CIP1, CDKN1, WAF1, CAP20, MDA 6
ProductDescription :
Rabbit monoclonal antibody [EPR3993] to p21
Background :
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1, p21, CDKN1A, WAF1) plays a critical role in the cellular response to DNA damage, and its overexpression results in cell cycle arrest . p21 binds to and inhibits CDK activity, preventing phosphorylation of critical CDK substrates and blocking cell cycle progression. p21 is suggested to possibly be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage . Endogenous cellular p21 is shown to be completely acetylated at its amino terminus and is therefore not a substrate for N-ubiquitylation .
Immunogen :
A synthetic peptide corresponding to residues in human p21 was used as an immunogen.
Clonality :
Monoclonal
Isotype :
IgG
TargetName :
p21
AntigenSpecies :
Human
ImmunogenRegion :
A synthetic peptide corresponding to residues in human p21 was used as an immunogen.
CalculatedMW :
21
AppliactionNote :
Recommended Starting Dilutions: . For WB: Use at a dilution of 1:1,000 - 10,000. For IHC: Use at a dilution of 1:250 - 500. For IP: Use at a dilution of 1:10 - 100. Optimal working dilution for a specific application should be determined by the investigator.
Reactivity :
Human, Rat
PackageUnit :
100 μl
Purification :
Cell Supernatant
Buffer :
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageInstruction :
Store at -20 °C. Stable for 12 months from date of receipt.
more info or order :
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
www.genetex.com
1-877-436-3839
headquarters: USA