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product summary
company name :
GeneTex
product type :
antibody
product name :
Glucokinase antibody [N1C1-2]
catalog :
GTX111517
quantity :
100.00μl
price :
299 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
product information
Catalog No :
GTX111517
Product Name :
Glucokinase antibody [N1C1-2]
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
100.00μl
List Price :
299 USD
Isotype :
IgG
Product Description :
Rabbit Polyclonal antibody to Glucokinase (glucokinase (hexokinase 4))
CrossReactivity :
Hu
Background :
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq]
Immunogen :
Recombinant protein encompassing a sequence within the center region of human Glucokinase. The exact sequence is proprietary.
Buffer :
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Uses :
ICC/IF, IHC-P, WB
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Image Legend_4 :
GCK antibody detects GCK protein by western blot analysis. A. 30 μg Huh7 whole cell lysate/extract. B. 30 μg Hep3B whole cell lysate/extract. C. 30 μg HepG2 whole cell lysate/extract. 10 % SDS-PAGE. GCK antibody (GTX111517) dilution: 1:1000
Image Legend_5 :
Glucokinase antibody [N1C1-2] detects Glucokinase protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Glucokinase protein stained by Glucokinase antibody [N1C1-2] (GTX111517) diluted at 1:500. Blue: Hoechst 33342 staining.
company information
GeneTex
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