Cortactin Antibody, phospho-specific (Tyr421) | EMD Millipore AB3852 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cortactin Antibody, phospho-specific (Tyr421)

catalog :

AB3852

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

application :

western blot

citations: 2

Reference
Nersesian S, Williams R, Newsted D, Shah K, Young S, Evans P, et al. Effects of Modulating Actin Dynamics on HER2 Cancer Cell Motility and Metastasis. Sci Rep. 2018;8:17243 pubmed publisher
Yu Y, Suryo Rahmanto Y, Lee M, Wu P, Phillip J, Huang C, et al. Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway. Oncogene. 2018;37:3778-3789 pubmed publisher

product information

Catalog Number :

AB3852

Subcategory :

Cell Structure

Product Name :

Anti-Cortactin Antibody, phospho-specific (Tyr421)

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q14247

Host Name :

Rabbit

Antigen :

Cortactin

Conjugate :

Affinity Purified

Product Description :

Anti-Cortactin Antibody, phospho-specific (Tyr421)

Cross Reactivity :

Human;Rat

Immunogen :

Rabbit anti-Cortactin (Y421) polyclonal antibody was raised against a peptide corresponding to residues surrounding phosphorylated Y421of human cortactin. The immunogen peptide is available for antibody blocking studies (Cat. No. AG985)

Specificity :

Recognizes Cortactin phosphorylated on tyrosine 421. Cortactin is an 80-85 kDa actin-binding protein, which consists of a variety of protein domains. The nature and function of these domains, coupled with the presence of multiple consensus sites for phosphorylation by tyrosine and serine/threonine kinases, suggests that cortactin integrates activation of specific signaling pathways with cytoskeletal reorganization.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months after receipt.