WNK4 Antibody | EMD Millipore 07-2263 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

WNK4 Antibody

catalog :

07-2263

quantity :

100 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Catalog Number :

07-2263

Subcategory :

Cell Signaling

Product Name :

Anti-WNK4 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q96J92

Host Name :

Rabbit

Antigen :

WNK4

Conjugate :

Affinity Purified

Product Description :

Anti-WNK4 Antibody

Cross Reactivity :

Human

Background :

WNK4 is a serine-threonine protein kinase that is commonly expressed in the distal nephron. Mutations in WNK1 and WNK4 cause pseudohypoaldosteronism type II, which causes hypertension, hyperkalemia, hyperchloremia and metabolic acidosis. WNK4 has been shown to decrease Na-Cl cotransporter activity and the potassium channel by removing it from the cell surface. It is thought that activating WNK4 inhibits the activity of WNK1. WNK4 has been shown to play a role in regulating blood pressure in addition to potassium homeostasis.

ALT Names :

WNK lysine deficient protein kinase 4;protein kinase, lysine deficient 4;Protein kinase with no lysine 4;serine/threonine-protein kinase WNK4;Protein kinase lysine-deficient 4

Immunogen :

KLH-conjugated linear peptide corresponding to the N-terminus of human WNK4.

Specificity :

This antibody recognizes WNK4 at the N-terminus.

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt