phospho PIX Antibody (Ser340) | EMD Millipore 07-2101 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho PIX Antibody (Ser340)

catalog :

07-2101

quantity :

100 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot

product information

Catalog Number :

07-2101

Subcategory :

Cell Signaling

Product Name :

Anti-phospho PIX Antibody (Ser340)

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9ES28

Host Name :

Rabbit

Antigen :

phospho PIX (Ser340)

Conjugate :

Affinity Purified

Isotype :

IgG

Product Description :

Anti-phospho PIX Antibody (Ser340)

Cross Reactivity :

Mouse

Background :

p-21-activated kinase (PAK) interacting exchange factor (PIX) is a guanine nucleotide exchange factor. PIX is a necessary component for the recruitment, regulation and activation of Rac1, as it is able to directly bind Rac1 via its SH3 domain. Studies indicate that PIX may also have an active role as a positive regulator of apoptosis, an inducer of membrane ruffling and in cell migration. Along with Rac1, PIX has been shown to regulate and interact with GIT1 and NOD2. Alternative splicing and initiation give rise to 8 known isoforms. Expression of PIX has been localized to the central nervous system. Isoforms B, C and E have highest expression in the testis and brain.

ALT Names :

Rho guanine nucleotide exchange factor (GEF) 7;PAK-interacting exchange factor beta;guanine nucleotide exchange factor 7;rho guanine nucleotide exchange factor 7;SH3 domain-containing proline-rich protein;p85;PAK3;Beta-Pix;P85COOL1;COOL-1;P85;PAK3BP;P50

Immunogen :

KLH-conjugated linear peptide corresponding to mouse PIX phosphorylated at Ser340.

Specificity :

This antibody recognizes PIX phosphorylated at Ser340.

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.