PDX1 (goat) Antibody | EMD Millipore 06-1385 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PDX1 (goat) Antibody

catalog :

06-1385

quantity :

100 µL

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; loading ...; fig s4d	Genovese G, Carugo A, TEPPER J, Robinson F, Li L, Svelto M, et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. 2017;542:362-366 pubmed publisher

product information

Catalog Number :

06-1385

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-PDX1 (goat) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P52946

Host Name :

Goat

Antigen :

PDX1 (goat)

Conjugate :

Serum

Product Description :

Anti-PDX1 (goat) Antibody

Cross Reactivity :

Mouse;Human

Background :

Transcription factor PDX1, also known as pancreatic and duodenal homeobox 1, activates expression of the insulin and somatostatin genes. This protein is a key regulator of islet peptide hormone expression and also plays an essential role in pancreatic development. It has been shown to interact with the basic helix-loop-helix domains of TCF3(E47) and NEUROD1 and with HMG-I(Y). This protein also interacts with the methyltransferase SETD7. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.

ALT Names :

pancreatic and duodenal homeobox 1;pancreatic-duodenal homeobox factor 1;somatostatin transcription factor 1;insulin promoter factor 1, homeodomain transcription factor;Insulin promoter factor 1;Somatostatin-transactivating factor 1;Insulin upstream factor 1;Glucose-sensitive factor;Islet/duodenum homeobox-1

Immunogen :

Recombinant protein corresponding to the N-terminus of mouse PDX1.

Specificity :

This antibody recognizes the N-terminus of PDX1.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.