product summary
request information :
company name :
Badrilla
product type :
antibody
product name :
 SERCA2a Rabbit Anti-Serum
catalog :
A010-20
quantity :
20 ul
price :
GBP184.46
clonality :
polyclonal
host :
rabbit
reactivity :
human, dog, mouse
application :
western blot
more info or order :
product information
Catalog Number :
A010-20
Product Name :
 SERCA2a Rabbit Anti-Serum
Host Species :
Rabbit
Clonality :
polyclonal
Product Type :
Polyclonal Ab
Size :
20 ul
List Price :
GBP184.46
Gene ID :
488
Product Description :
Polyclonal antibody specific to SERCA2a
CrossReactivity :
The antibody recognises SERCA2a and binding is blocked in the presence of a peptide containing the epitope. The antibody reacts with SERCA2a from human, rat, mouse, rabbit, canine, and bovine species
SpeciesSummary :
The antibody reacts with SERCA2a from human, rat, mouse, rabbit, canine, and bovine species
Background :
SERCA2a is a Ca2+ pump located in the sarcoplasmic reticulum of cardiac and slow-twitch skeletal muscle. The enzyme transports Ca2+ from the cytoplasm into the SR using the hydrolysis of ATP as the energy source for this reaction. Two Ca2+ are transported for each ATP hydrolysed.  This Ca2+ transport is the principal means of muscle relaxation in cardiac and slow-twitch skeletal muscle. The activity of SERCA2a is moderated by its interaction with phospholamban. SERCA2a is one isoform of SERCA2: this isoform differs from SERCA2b and SERCA2c at the extreme carboxy terminus only.  Antibody A010-20 recognises the C-terminal sequence which distinguishes SERCA2a from SERCA2b and SERCA2c. 
Immunogen :
Synthetic peptide (C-LEPAILE997) corresponding to amino acids at the extreme C-terminus of SERCA2a
Specificity :
The antibody recognises SERCA2a and binding is blocked in the presence of a peptide containing the epitope. The antibody reacts with SERCA2a from human, rat, mouse, rabbit, canine, and bovine species
Purity :
Raw Serum
Preservative :
Lyophilised:
Packaging :
0.5 ml Cryovial
Uses :
WB
Application Summary :
WB (1:5000)
Storage :
Lyophilised antibody is stable at 4 °C when stored with desiccant. Reconstitute lyophilised powder in 20 ul of 18 MΩ H2O, aliquot and store frozen at -80 °C for 1 year. Avoid freese - thaw cycles
Product References :
Colyer, J., & Wang J.H. (1991) J. Biol. Chem. 266, 17486-17493
more info or order :
company information
Badrilla
Leeds Innovation Centre
103 Clarendon Road
Leeds, LS2 9DF
info@badrilla.com
www.badrilla.com
011334 31869
headquarters: UK
Badrilla Ltd. is a biotechnology company founded in 2003 and located in Leeds, UK. Badrilla makes and distributes exceptional monoclonal and polyclonal antibodies to cardiovascular protein and phospho-protein targets. We source excellent antibodies from academic leaders and re-validate antibodies not made by ourselves in assays of relevance to our customers. Working with outstanding academic collaborators, we are developing new technologies to calibrate immunoassays, which will enable the performance of genuinely Quantitative Western blotting, Quantitative biomarker measurement, and Quantitative diagnostics. Our aim is to provide products that work first time in the applications you deploy, which accelerate the progress of your research, and which satisfy your expectations in every way.