This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCEFL3xHAmGli2
catalog :
37671
citations: 4
Reference
Wu F, Zhang C, Zhao C, Wu H, Teng Z, Jiang T, et al. Prostaglandin E1 Inhibits GLI2 Amplification-Associated Activation of the Hedgehog Pathway and Drug Refractory Tumor Growth. Cancer Res. 2020;80:2818-2832 pubmed publisher
Liu Y, Kim H, Dong E, Dong C, Huang M, Liu Y, et al. Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway. Biochim Biophys Acta Mol Basis Dis. 2019;1865:2685-2693 pubmed publisher
Moore B, Stepanchick A, Tewson P, Hartle C, Zhang J, Quinn A, et al. Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics. Proc Natl Acad Sci U S A. 2016;113:13069-13074 pubmed
Kim J, Kato M, Beachy P. Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus. Proc Natl Acad Sci U S A. 2009;106:21666-71 pubmed publisher
product information
Catalog Number :
37671
Product Name :
pCEFL3xHAmGli2
article :
doi10.1073/pnas.0912180106
id5539
pubmed_id19996169
bacterial resistance :
Ampicillin
cloning :
backbonepCEFL
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3unknown
cloning_site_5unknown
promoterEF1a
sequencing_primer_3BGH-Rev
sequencing_primer_5EF1a-Fwd
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
geneGli2
id14633
genbank_ids
mutation
nameGli2
shRNA_sequence
size
species
10090
Mus musculus
tags
locationN terminal on insert
tag3xHA
plasmid copy :
pCEFL was provided by J. Silvio Gutkind (National Institutes of Health).
resistance markers :
756
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA