This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLenti6/V5/DEST-VPS35
catalog :
21691
citations: 4
Reference
Rahman A, Soto Avellaneda A, Yong Jin H, Stojkovska I, Lai N, Albright J, et al. Enhanced Hyaluronan Signaling and Autophagy Dysfunction by VPS35 D620N. Neuroscience. 2020;441:33-45 pubmed publisher
Williams E, Glauser L, Tsika E, Jiang H, Islam S, Moore D. Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting. Hum Mol Genet. 2018;27:3189-3205 pubmed publisher
Tsika E, Glauser L, Moser R, Fiser A, Daniel G, Sheerin U, et al. Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration. Hum Mol Genet. 2014;23:4621-38 pubmed publisher
Scott K, Kabbarah O, Liang M, Ivanova E, Anagnostou V, Wu J, et al. GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer. Nature. 2009;459:1085-90 pubmed publisher
product information
Catalog Number :
21691
Product Name :
pLenti6/V5/DEST-VPS35
article :
doi10.1038/nature08109
id2727
pubmed_id19553991
bacterial resistance :
Ampicillin
cloning :
backbonepLenti6/V5/DEST
backbone_mutation
backbone_originInvitrogen
backbone_size2391
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
Other
Invitrogen Gateway Destination vector
growth temp :
Invitrogen stbl3
origin :
37
pi :
alt_names
VPS35
cloning
clone_methodGateway Cloning
cloning_site_3att
cloning_site_5att
promoter
sequencing_primer_3V5R
sequencing_primer_5CMVF
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMEM3, PARK17
geneVPS35
id55737
genbank_ids
NM_018206
mutation
nameVacuolar Protein Sorting 35 homolog
shRNA_sequence
size2391
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagV5
resistance markers :
78
tags :
Unknown
terms :
Blasticidin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA