ER alpha Antibody | Abgent AJ1268b product information

product summary

request information :

company name :

Abgent

product type :

antibody

product name :

ER alpha Antibody

catalog :

AJ1268b

quantity :

100 ul

price :

290.00 USD

clonality :

monoclonal

host :

rabbit

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Abgent product webpage

product information

CatalogCode :

AJ1268b

product name :

ER alpha Antibody

host species :

rabbit

clonality :

monoclonal

product type :

Primary Antibody

Size :

100 ul

List Price :

290.00 USD

Clone :

EPR703(2)

Product Description :

Rabbit Monoclonal Antibody

CrossReactivity :

Background :

Estrogen receptor alpha (ER alpha) is a nuclear protein and member of the steroid hormone receptor family. ER alpha possesses both DNA binding and ligand binding domains, and exerts a significant role in activating the transcription of certain genes (1). Ligand-dependent dimerization and phosphorylation both function to regulate the transcriptional activation of ER alpha (2). The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy (3).

ALTnames :

ESR1, ESR, NR3A1, Estrogen receptor, Estradiol receptor;ER-alpha;Nuclear receptor subfamily 3 group A member 1

Immunogen :

A synthetic peptide corresponding to residues on the C-terminus of human ERalpha was used as immunogen.

buffer :

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Application Summary :

WB, IHC

Storage :

ER alpha Antibody can be stored at -20°C for up to 12 months from time of receipt.

more info or order :

Abgent product webpage