Abgent

antibody

ER alpha Antibody

AJ1268a

100 ul

290.00 USD

monoclonal

rabbit

human, rat, mouse

western blot, immunohistochemistry, immunocytochemistry

AJ1268a

ER alpha Antibody

rabbit

monoclonal

Primary Antibody

100 ul

290.00 USD

E115

Rabbit Monoclonal Antibody

H, M, R

Estrogen receptor alpha (ER alpha) is a nuclear protein and member of the steroid hormone receptor family. ER alpha possesses both DNA binding and ligand binding domains, and exerts a significant role in activating the transcription of certain genes (1). Ligand-dependent dimerization and phosphorylation both function to regulate the transcriptional activation of ER alpha (2). Particularly, phosphorylation of serines 104 and 106, located in the N-terminal transcription activation function-1 domain (AF-1), plays a large role in regulating ER alpha activity (3).

ESR1, ESR, NR3A1, Estrogen receptor, Estradiol receptor;ER-alpha;Nuclear receptor subfamily 3 group A member 1

A synthetic peptide corresponding to residues in human ERalpha was used as immunogen.

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

WB, IHC, ICC

ER alpha Antibody can be stored at -20°C for up to 12 months from time of receipt.