mRNA Processing
gene
reagent
sample publication
sample review
total:1
Subcellular distribution of ADAR1 isoforms is synergistically determined by three nuclear discrimination signals and a regulatory motif. 2004 to the paper
Santa Cruz Biotechnology anti-mouse ADAR1 antibody was used in western blot to study the intracellular distribution of the various ADAR1 isoforms.
total:1
Human scavenger receptor class B type II (SR-BII) and cellular cholesterol efflux. 2004 to the paper
Novus Biologicals anti-RED-1 antibody was used in flow cytometry to study human scavenger receptor class B type II (SR-BII) and cellular cholesterol efflux.
total:2
THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo. 2010 to the paper
Santa Cruz monoclonal antibodies against Aly/THOC4 were used in western blot to investigate the role of THOC5/Fms in the maintenance of hematopoiesis and the regulation of THOC1. more
total:1
Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. 2001 to the paper
Jackson Immunoresearch Laboratories anti-ACF (4-18) antibody was used in western blot to study the role of RNA-binding protein CUGBP2 in mammalian RNA ending.
total:3
Combinatorial control of signal-induced exon repression by hnRNP L and PSF. 2007 to the paper
BioLegend anti-hnRNPD polyclonal antibody was used in western blot in order to investigate the mechanisms of hnRNP L and PSF combinatorial control over the exon repression through signal-induced alternative splicing. more
total:1
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. 2009 to the paper
Bethyl Laboratories rabbit anti-CCAR1 antibody (1:10,000) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to prove that the association of AKAP350A and CCAR1 with RNA stress granules is microtubule dependent.
total:3
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. 2005 to the paper
Santa Cruz Biotechnology cyclin H antibody was used in western blot to study the role of Dmp1 in Ras-Raf-Arf signaling. more
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK7 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:1
The 3' ends of human pre-snRNAs are produced by RNA polymerase II CTD-dependent RNA processing. 2003 to the paper
Santa Cruz anti-CPSF 160 antibody
(1:500) was used in western blot in order to demonstrate that the 3' end of human pre-snRNAs is produced by RNA processing rather than by termination of transcription.
total:1
The 3' ends of human pre-snRNAs are produced by RNA polymerase II CTD-dependent RNA processing. 2003 to the paper
Santa Cruz anti-CstF 64 antibody
(1:500) was used in western blot in order to demonstrate that the 3' end of human pre-snRNAs is produced by RNA processing rather than by termination of transcription.
total:1
Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selection. 2005 to the paper
Christine Milcarek (University of Pittsburgh) anti-CstF-77 antibody was used in western blot to demonstrate that CstF-64 influence gene expression and induce alternative poly (A) site selection..
total:3
Nuclear DNA helicase II is recruited to IFN-alpha-activated transcription sites at PML nuclear bodies. 2002 to the paper
Dr. S. Zhang (Institute of Molecular Biotechnology, Jena, Germany) rabbit polyclonal anti NDH II antibody was used in western blot and immunohistochemistry to study the role of nuclear dna helicase II in IFN-alpha activated transcription sites at PML nuclear bodies. more
total:36
The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation. 2010 to the paper
Cell Signaling Technology eIF4E antibody was used in western blot in order to identify the 4E-BP as a relatively poor direct substrate for the Parkinson's disease associated LRRK2. more
total:2
Biochemical analysis of the damage recognition process in nucleotide excision repair. 2003 to the paper
Santa Cruz Biotechnology anti-XPD antibody was used in western blot to study the damage recognition process in nucleotide excision repair more
total:4
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Santa Cruz anti-XPB antibody was used to perform western blot in order to study the DNA damage and response by UV. more
total:6
A yeast model of FUS/TLS-dependent cytotoxicity. 2011 to the paper
Abcam anti-FUS antibody (1:1000) was used to perform western blot in order to study the FUS/TLS-dependent cytotoxicity in yeast. more
total:3
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 to the paper
Santa Cruz anti-TFIIF antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes. more
total:3
Casein kinase 2 interacts with cyclin-dependent kinase 11 (CDK11) in vivo and phosphorylates both the RNA polymerase II carboxyl-terminal domain and CDK11 in vitro. 2003 to the paper
Santa Cruz Biotechnology anti-TFIIH p62 antibody was used in western blot to study the characterization of CDK11p110 signaling and protein complexes and the role they play in transcription and RNA processing. more
total:1
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. 2009 to the paper
Santa Cruz Biotechnology TFIIH antibody was used in western blot to study the regulation of aromatase transcription and estrogen biosynthesis in adipose stromal cells (ASCs).
total:1
Thrombopoietin induces HOXA9 nuclear transport in immature hematopoietic cells: potential mechanism by which the hormone favorably affects hematopoietic stem cells. 2004 to the paper
Santa Cruz Biotechnology rabbit antibody to TFIIH was used in western blot to identify the induction of HOXA9 nuclear transport by thrombopoietin in immature hematopoietic cells as the potential mechanism by which the hormone favorably affects hematopoietic stem cells.
total:10
Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer. 2009 to the paper
Santa Cruz anti-hnRNP C1/C2 Ab was used to detect hnRNP C1/C2 in western blot in order to find out the novel mechanism by which eIF4E levels are regulated at the level of mRNA stability more
total:8
Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis. 2008 to the paper
Sigma monoclonal anti-hnRNP-A1 antibody was used to perform immunoprecipitation in order to study the relevant role of RNA binding proteins(RBPs) in posttranscriptional regulation of CML development and progression. more
total:2
Regulation of gamma-fibrinogen chain expression by heterogeneous nuclear ribonucleoprotein A1. 2005 to the paper
Abcam mouse monoclonal hnRNP A2B1 antibody was used in EMSA to study gamma-fibrinogen expression more
total:2
Proteomic identification of proteins associated with the osmoregulatory transcription factor TonEBP/OREBP: functional effects of Hsp90 and PARP-1. 2007 to the paper
Santa Cruz Biotechnology hnRNP F (sc-10045) antibody was used in western blot (1:200) and EMSA to identify proteins associated with the osmoregulatory transcription factor TonEBP/OREBPstudy more
total:2
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. 2010 to the paper
Abcam anti-hnRNP H antibody was used to perform western blot in order to study the interaction between TDP-43 and proteins that regulate RNA metabolism. more
total:6
Proteomic and genomic analysis of PITX2 interacting and regulating networks. 2009 to the paper
Epitomics anti-hnRNP K antibody was used to perform western blot in order to find out the PITX2 interacting and regulating networks. more
total:3
Combinatorial control of signal-induced exon repression by hnRNP L and PSF. 2007 to the paper
Abcam anti-hnRNP L antibody was used in western blot in order to investigate the mechanisms of hnRNP L and PSF combinatorial control over the exon repression through signal-induced alternative splicing. more
total:2
Proteomic and genomic analysis of PITX2 interacting and regulating networks. 2009 to the paper
Abcam anti-hnRNP U antibody was used to perform western blot in order to find out the PITX2 interacting and regulating networks. more
total:1
Influenza virus targets the mRNA export machinery and the nuclear pore complex. 2007 to the paper
Proteintech Group anti-E1B-AP5 antibody was used in western blot in order to study the mechanisms used by influenza A virus to disrupt the mRNA nuclear export machinery.
total:3
The exon junction complex component Magoh controls brain size by regulating neural stem cell division. 2010 to the paper
Proteintech anti-Magoh antibody was used to perform immunohistochemical assays in order to study the genetic mechanisms of Magoh in controlling brain size. more
total:2
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". 2006 to the paper
Santa Cruz monoclonal anti-Mat1 antibody (F-6) was used in human T98G cells and in western blot to study the role for cyclins and CDK "inhibitors" in Thr172 phosphorylation of CDK4. more
total:2
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Protein-Tech anti-CBP80 antibody was used in western blot in order to investigate the function of surveillance complex associated with ribosome during nonsense-mediated mRNA decay (NMD). more
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abgent CBP20 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:4
Nuclear export factor RBM15 facilitates the access of DBP5 to mRNA. 2009 to the paper
Santa Cruz anti-NXF1 antibody was used to perform immunohistochemistry in order to study the role of nuclear export factor RBM15 in the contact of the DBP5 and mRNA. more
total:1
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-the large subunit of RNA polymerases II antibody (N20) was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis.
total:3
Developmentally specific role of the CCAAT box in regulation of human gamma-globin gene expression. 2004 to the paper
Santa Cruz Biotechnology anti-Pol II (Pol II (N-20) antibody sc-899 was used in ChIP assay to study the regulation of CCAAT box of human gamma-globin gene expression during development. more
total:1
Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome. 2007 to the paper
Santa Cruz Biotechnology anti-Prp8 was used in immunoprecipitation to isolate Prp8 and in western blot to detect Prp8 in HeLa cells
total:1
Alternative splicing of the multidrug resistance protein 1/ATP binding cassette transporter subfamily gene in ovarian cancer creates functional splice variants and is associated with increased expression of the splicing factors PTB and SRp20. 2004 to the paper
Oncogene Research Products monoclonal anti-PTB antibody was used in western blot to detect PTB in human ovarian tumor tissues.
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Sigma Y14 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:69
RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. 2011 to the paper
Santa Cruz anti-Rpb1 was used to perform western blot and ChIP assay in order to show that histone mRNA 3 end processing needs the phosphorylation of RNAP II CTD Thr4. more
total:1
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells. 2002 to the paper
Dr Michael H. Wu anti-hCE-1 antibody was used in western blot to study the irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.
total:17
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. 2010 to the paper
Sigma mouse anti-SC35 antibody (1:5000) was used to perform immunofluorescence in order to study knockdown of TDP-43 mediated HDAC6 downregulation. more
total:1
CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. 2009 to the paper
Proteintech Group Rabbit polyclonal anti-SF3b 145 was used to carry out western blot analysis in order to investigate the mechanism for CUGBP2 activating cardiac troponin T exon 5 inclusion
total:1
CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. 2009 to the paper
Proteintech Group Rabbit polyclonal anti-SF3b49 was used to carry out western blot analysis in order to investigate the mechanism for CUGBP2 activating cardiac troponin T exon 5 inclusion
total:14
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination. 2010 to the paper
Novus rabbit anti-SMC1 antibody was used to carry out ChIP assays in order to investigate the mechanism for PTIP promoting specific chromatin changes and immunoglobulin class-switch recombination. more
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Abcam rabbit anti-U1A antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing.
total:4
The honey bee epigenomes: differential methylation of brain DNA in queens and workers. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-SmB/B' antibody (sc-271094) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
total:1
Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein. 2001 to the paper
The Binding Site human autoimmune serum (ENA anti-Sm) reactive against Sm-D was used in western blot to study the association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein
total:3
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 to the paper
Santa Cruz Biotechnology mouse monoclonal B-Raf antibody was used in western blot in order to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell lines more
total:5
SRp20 and CUG-BP1 modulate insulin receptor exon 11 alternative splicing. 2009 to the paper
ATCC a culture supernatant from hybridoma cells expressing antibodies to SRp20 (CRL-2384) was used for immunodepletion of HeLa nuclear extracts in order to study the roles for SRp20 and CUG-BP1 in modulating insulin receptor exon 11 alternative splicing. more
total:1
Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal anti-SRm160 antibody K15 was used in western blot to study the association of SRm160-containing complexes with cohesin.
total:4
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Zymed mouse anti-SF2/ASF antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing. more
total:1
Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells. 2003 to the paper
Zymed monoclonal SR protein antibody (recognizing a subset of non-snRNP splicing factors (SR proteins) 20 21 such as SRp75, SRp55, SRp40, and SRp20 but not SRp30-a or b (SC-35), SRm300, or Pnn) was used in western blot and immunohistochemistry to study the interaction between Pinin/DRS/memA with SRp75, SRm300 and SRrp130 in corneal epithelial cells
total:4
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
Santa Cruz Biotechnology HRS rabbit polyclonal antibody (M-79) was used to perform western blot in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS. more
total:1
Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells. 2003 to the paper
Zymed monoclonal SR protein antibody (recognizing a subset of non-snRNP splicing factors (SR proteins) 20 21 such as SRp75, SRp55, SRp40, and SRp20 but not SRp30-a or b (SC-35), SRm300, or Pnn) was used in western blot and immunohistochemistry to study the interaction between Pinin/DRS/memA with SRp75, SRm300 and SRrp130 in corneal epithelial cells
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
BD Bioscience mouse anti-9G8 antibody was used to perform immunoprecipitation in order to study the elongation of RNA Polymerase II during co-transcriptional splicing.
total:2
Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression. 2007 to the paper
Santa Cruz Biotechnology anti-Spt5 (sc-28678) antibody was used in western blot to study the role of transcription termination factor Pcf11 on the processivity of Pol II more
total:2
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Abcam rabbit anti-U2AF65 antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing. more
total:5
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Cell Signalling YB-1 antibody (1:200) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more