Muscle contraction
gene
reagent
sample publication
sample review
ACTN2
actinin, alpha 2
total:3
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) binds to alpha-actinin 1: novel pathways in skeletal muscle?. 2008 to the paper
Sigma monoclonal anti-alpha-actinin-2 antibody was used in immunohistochemistry to study the role for the binding of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) with alpha-actinin 1 in skeletal muscle. more
ACTN3
actinin, alpha 3
total:4
Functional cardiomyocytes derived from human induced pluripotent stem cells. 2009 to the paper
Sigma monoclonal anti actinin was used to perform immunolabeling in order to study functional cardiomyocytes derived from human induced pluripotent stem cells. more
alpha myosin heavy chain
myosin, heavy chain 6, cardiac muscle, alpha
total:5
Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic?. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-human muscle myosin antibody was used in immunohistochemistry to study the cells ability for migration, engraftment, myogenic potential, and expression of human dystrophin in affected muscles and the efficiency comparison of single and serial early transplantation. more
CALD1
caldesmon 1
total:3
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Lab Vision anti-caldesmon antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
desmin
total:26
ATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of Purkinje neurons in the juvenile human brain. 2007 to the paper
Epitomics rabbit anti-ATM monoclonal antibody(1:100) was used to perform immunofluoresence in order to study the mechanism of genetic disease ataxia telangiectasia (AT) in the nucleus of human Purkinje neurons. more
dystrophin
total:8
Long-term survival of transplanted stem cells in immunocompetent mice with muscular dystrophy. 2008 to the paper
Novacastra anti-dystrophin mouse monoclonal antibody NCL-DYS2 was used in immunohistochemistry at 1:100 in order to study the role of duchenne muscular dystrophy in the long-term survival of transplanted stem Cells more
ITGA1
integrin, alpha 1
total:11
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha1 antibody (clone FB12) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
ITGB5
integrin, beta 5
total:9
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. 2008 to the paper
Chemicon alphaVbeta5 mAb was used to perform immunoblotting in order to illustrate that transforming growth factor, beta-induced (beta ig-h3/TGFBI) could enhance the aggressiveness and alter the metastatic properties of colon cancer cells in vivo. more
MYBPC1
myosin binding protein C, slow type
total:1
Relationship between neural crest cells and cranial mesoderm during head muscle development. 2009 to the paper
Developmental Studies Hybridoma Bank monoclonal anti-meromyosin antibody was used to carry out immunochemistry assays in order to investigate the relationship between neural crest cells and muscle progenitor cells during branchial arch development.
MYBPC3
myosin binding protein C, cardiac
total:1
Prox1 maintains muscle structure and growth in the developing heart. 2009 to the paper
Obinata anti-cardiac MyBPC was used to perform immunohistochemistry in order to show that Prox1 plays an important role in maintaining the muscle structure and growth of developing heart.
MYH11
myosin, heavy chain 11, smooth muscle
total:7
Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue. 2008 to the paper
Sigma-Aldrich monoclonal anti-human smooth muscle myosin antibody was used for western blot in order to show that ILK can regulate airway smooth muscle differentiation. more
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
total:1
Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles. 2003 to the paper
Alan Kelly (University of Chicago, Chicago, IL) anti-MYH3 antibody (N.2.262) was used in immunohistochemistry to study its expression in human extraocular muscles
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
MYL1
myosin, light chain 1, alkali; skeletal, fast
total:6
Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway. 2004 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-MLC antibody was used in western blot to detect MLC in NR6 WT cells and NR6 c'973 cells. more
MYL2
myosin, light chain 2, regulatory, cardiac, slow
total:10
Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma. 2008 to the paper
Cell Signaling mouse monoclonal anti-phospho-myosin light chain 2 was used to perform immunocytochemistry in order to show that Rho/ROCK/MLC pathway could be inhibited by DCL1 in hepatocellular carcinoma. more
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
total:3
Essential myosin light chain as a target for caspase-3 in failing myocardium. 2002 to the paper
Biocytex mouse monoclonal vMLC1 (clones F109.16A12 and F109.17A5) antibody was used in western blot and immunocytochemistry to study its degradation by caspase-3 in failing myocardium more
MYL4
myosin, light chain 4, alkali; atrial, embryonic
MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
MYLK
myosin light chain kinase
total:3
A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability. 2004 to the paper
Sigma-Aldrich anti-MLCK1 antibody was used in western blot to study the role of a differentiation-dependent splice variant of myosin light chain kinase (MLCK1). more
nebulin
total:1
Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms. 2004 to the paper
Sigma nebulin (NB2) antibody was used in western blot to study the effect of mutant actin isoforms in ACTA1 nemaline myopathy
paxillin
total:51
Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma. 2008 to the paper
Upstate mouse monoclonal anti-paxillin was used to perform immunocytochemistry in order to show that Rho/ROCK/MLC pathway could be inhibited by DCL1 in hepatocellular carcinoma. more
smooth muscle actin
actin, alpha 2, smooth muscle, aorta
total:33
Hepatoblast and mesenchymal cell-specific gene-expression in fetal rat liver and in cultured fetal rat liver cells. 2009 to the paper
Epitomics Rabbit polyclonal anti-SMA antibody was used to carry out immunofluorescence assays in order to determine whether passaged rat fetal liver cells are functional hepatoblasts. more
SORBS1
sorbin and SH3 domain containing 1
Talin
talin 1
total:10
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Serotec anti-talin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
titin
total:2
Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy. 2007 to the paper
Siegfried Labeit (Universit tsklinikum Mannheim) anti-titin N2B (1:200) antibody was used in immunohistochemistry to study the role of the titin N2B region in systole and diastole of the heart. more
TMOD1
tropomodulin 1
total:1
The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes. 2003 to the paper
C. Grant (Custom Monoclonals) Tmod1 antibody was used in western blot to study the interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes.
TNNI1
troponin I type 1 (skeletal, slow)
total:4
Cell-cell and cell-extracellular matrix interactions regulate embryonic stem cell differentiation. 2007 to the paper
Abcam cardiac troponin antibody was used in immunohistochemistry (1:50) to determine the role of exogenous and endogenous ECM in the differentiation of nonhuman primate ESCs. more
TNNI2
troponin I type 2 (skeletal, fast)
total:1
Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms. 2004 to the paper
University of Iowa hybridoma bank monoclonal troponin Ifast (MynT-fast) antibody was used in western blot to study the effect of mutant actin isoforms in ACTA1 nemaline myopathy
TNNI3
troponin I type 3 (cardiac)
total:5
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Cell Signaling Technology phosphoSer23, 24-TnI antibody was used in western blot in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
TNNT1
troponin T type 1 (skeletal, slow)
total:1
Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms. 2004 to the paper
University of Iowa hybridoma bank monoclonal troponin Tslow (CT3) antibody was used in western blot to study the effect of mutant actin isoforms in ACTA1 nemaline myopathy
TNNT2
troponin T type 2 (cardiac)
total:3
Functional cardiomyocytes derived from human induced pluripotent stem cells. 2009 to the paper
Thermo Scientific monoclonal anti-cTnT was used to perform immunolabeling in order to study functional cardiomyocytes derived from human induced pluripotent stem cells. more
TPM1
tropomyosin 1 (alpha)
total:4
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Sigma anti-tropomyosin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
vimentin
total:76
Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-vimentin (C-20 and H-84, 1:1000) antibody was used to perform western blot in order to study the formation mechanism of tubulin-based microtentacles in detached breast tumor cells. more
vinculin
total:54
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
Sigma mouse anti-vinculin antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more