Membrane Trafficking
gene
reagent
sample publication
sample review
14 3 3 protein beta alpha
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
total:9
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3beta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
14 3 3 protein epsilon
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
total:5
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Santa Cruz Biotechnology anti-14-3-3epsilon antibody (1:2000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
14 3 3 protein gamma
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
total:3
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3gamma antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
14 3 3 protein tau
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
total:21
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Santa Cruz Biotechnology anti-14-3-3 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
14 3 3 protein zeta
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
total:6
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3zeta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
Akt
v-akt murine thymoma viral oncogene homolog 1
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
AKT2
v-akt murine thymoma viral oncogene homolog 2
total:15
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. 2009 to the paper
Cell Signaling anti-p-Akt Ser473 antibody was used in immunohistochemistry in order to investigate the mechanism of how Akt mediates sterol regulatory element-binding protein 1 (SREBP-1) cleavage induced by EGFR. more
alpha myosin heavy chain
myosin, heavy chain 6, cardiac muscle, alpha
total:5
Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic?. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-human muscle myosin antibody was used in immunohistochemistry to study the cells ability for migration, engraftment, myogenic potential, and expression of human dystrophin in affected muscles and the efficiency comparison of single and serial early transplantation. more
AMPK
protein kinase, AMP-activated, beta 1 non-catalytic subunit
total:14
The ancient drug salicylate directly activates AMP-activated protein kinase. 2012 to the paper
Cell Signalling anti-pAMPK was used to perform western blot in order to show that AMPK could be activated by salicylate directly. more
AP1B1
adaptor-related protein complex 1, beta 1 subunit
total:3
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1g antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
AP1M1
adaptor-related protein complex 1, mu 1 subunit
AP1M2
adaptor-related protein complex 1, mu 2 subunit
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
V. Faundez anti-sigma3-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
AP2M1
adaptor-related protein complex 2, mu 1 subunit
total:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 to the paper
BD Biosciences monoclonal anti-AP50 antibody was used in human HeLa cells or HUVECs and in western blot to study the role for clathrin adaptor AP2 in regulating thrombin receptor constitutive internalization and endothelial cell resensitization. more
AP3B1
adaptor-related protein complex 3, beta 1 subunit
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
V. Faundez anti-deta3-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
AP4B1
adaptor-related protein complex 4, beta 1 subunit
AP4E1
adaptor-related protein complex 4, epsilon 1 subunit
total:1
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti- AP4e antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis.
ARF1
ADP-ribosylation factor 1
total:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 to the paper
Affinity Bioreagents anti-Arf antibody was used to perform western blot in order to study the interaction between Arf and Poliovirus Protein 3CD and its effect on poliovirus replication. more
ARFGAP1
ADP-ribosylation factor GTPase activating protein 1
ARRB1
arrestin, beta 1
total:7
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
Santa Cruz Biotechnology beta-arrestin1/2 rabbit polyclonal antibody (21-B1) was used to perform western blot in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS. more
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
beta-COP
coatomer protein complex, subunit beta 1
total:16
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents beta-COP antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
BLOC1S3
biogenesis of lysosomal organelles complex-1, subunit 3
BLOC1S4
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
E. Dell'Angelica anti-Pallidin in antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
CHMP2B
charged multivesicular body protein 2B
total:1
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. 2011 to the paper
Abcam antibody mouse rabbit anti-CHMP2B antibody was used to perform immunohistochemistry in order to study quantification of CHMP2B on intercellular bridges at different stages.
CHMP3
charged multivesicular body protein 3
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-Vps24 antibody was used in western blot to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
CHMP4A
charged multivesicular body protein 4A
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-CHMP4A was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
CHMP4B
charged multivesicular body protein 4B
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-CHMP4B was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
CHMP7
charged multivesicular body protein 7
CI-MPR
insulin-like growth factor 2 receptor
total:7
Vaccinia virus p37 interacts with host proteins associated with LE-derived transport vesicle biogenesis. 2009 to the paper
Affinity BioReagents CI-MPR was used as primary antibody in immunofluorecent staining in order to study the interaction between the vaccinia virus p37 and host proteins associated with LE-derived transport vesicle biogenesis. more
Clathrin Heavy Chain
clathrin, heavy chain (Hc)
total:28
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Millipore rabbit anti-Clathrin antibody was used to perform immunoelectron microscopy in order to investigate the mechanism of Golgi-mediated protein traffic. more
CLTA
clathrin, light chain A
total:5
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Sigma-Aldrich monoclonal anti-clathrin light chain antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
CLTCL1
clathrin, heavy chain-like 1
total:2
Association of the Hermansky-Pudlak syndrome type-3 protein with clathrin. 2005 to the paper
BD Biosciences Pharmingen mouse monoclonal anti-clathrin heavy chain antibody was used in western blot and immunocytochemistry to study the association of the Hermansky-Pudlak syndrome type-3 protein with clathrin. more
COPA
coatomer protein complex, subunit alpha
total:3
Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL protein. 2007 to the paper
Affinity BioReagents anti-alpha-COP I antibody was used to perform western blot in order to study the interaction between SARS-CoV with Bcl-XL to result in cell apoptosis. more
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
total:6
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 to the paper
Novus Biologicals anti- beta-COP antibody was used in immunocytochemistry in order to investigate the mechanism of an autonomous cholesterol regulation activated by adenovirus membrane protein RID-alpha. more
COPE
coatomer protein complex, subunit epsilon
COPG1
coatomer protein complex, subunit gamma 1
total:1
Transport of the IgE receptor alpha-chain is controlled by a multicomponent intracellular retention signal. 2006 to the paper
Santa Cruz Biotechnology anti-gamma-COPI antibody (sc-14167) was used in human HEK293 cells and in western blot to study the role of the multicomponent intracellular retention signal in controlling transport of the IgE receptor alpha-chain.
COPZ1
coatomer protein complex, subunit zeta 1
CPD
carboxypeptidase D
total:1
Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair. 2007 to the paper
MBL International mouse anti-CPD was used to perform western blot in order to investigate the role of XPC protein in the initiation of nucleotide excision repair.
Cx43
gap junction protein, alpha 1, 43kDa
total:20
CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus. 2009 to the paper
Santa Cruz Biotech polyclonal goat anti-connexin 43 antibody was used in immunohistochemistry in order to demonstrate that the normal human cornea is equipped with a molecular tool to actively metabolize NAD+, helping maintain corneal homeostasis more
Dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
total:10
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension. 2011 to the paper
Santa Cruz antibody polyclonalanti-Dab2 antibody was used to perform immunohistochemistry in order to study the expression of KCNJ5 in adrenal glomerulosa. more
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
DNM2
dynamin 2
total:6
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells. 2007 to the paper
BD Biosciences anti-dynamin-2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism of entry for Chlamydia trachomatis into nonphagocytic cells. more
DTNBP1
dystrobrevin binding protein 1
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
E. Dell'Angelica anti-Dysbindin in antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
Dynamin
dynamin 1
total:15
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Santa Cruz Biotechnology monoclonal anti-dynamin 1 antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
EAP20
vacuolar protein sorting 25 homolog (S. cerevisiae)
EAP45
vacuolar protein sorting 36 homolog (S. cerevisiae)
EXOC4
exocyst complex component 4
total:1
Genetic analysis of the subunit organization and function of the conserved oligomeric golgi (COG) complex: studies of COG5- and COG7-deficient mammalian cells. 2005 to the paper
BD Biosciences anti-Sec8 antibody was used in western blot to study the Subunit organization and function of the conserved oligomeric golgi (COG) complex.
FTH1
ferritin, heavy polypeptide 1
total:5
PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element. 2007 to the paper
Santa Cruz Biotechnology anti-ferritin H antibody was used to perform western blot in order to investigate the role of PIAS3 in the ARE-mediated transcription of the ferritin H gene. more
FTL
ferritin, light polypeptide
total:3
Control of iron homeostasis by an iron-regulated ubiquitin ligase. 2009 to the paper
Sigma anti-ferritin antibody was used to perform western blot in order to study the roles of the iron-regulated ubiquitin ligase in the regulation towards the iron homeostasis. more
GAK
cyclin G associated kinase
total:1
The DnaJ-domain protein RME-8 functions in endosomal trafficking. 2005 to the paper
MBL International mouse monoclonal antibody against auxilin 2 (also known as cyclin-G-associated kinase) was used in western blot to study the function of a DnaJ domain-containing protein RME-8 in endosomal trafficking.
gamma-adaptin
adaptor-related protein complex 1, gamma 1 subunit
total:15
Adaptor heat shock protein complex formation regulates trafficking of the asialoglycoprotein receptor. 2006 to the paper
Sigma mouse monoclonal anti-gamma-subunit of AP1 antibody was used in western blot to study the effect of adaptor heat shock protein complex formation on trafficking of the asialoglycoprotein receptor in HuH-7 and Trf1 human hepatoma cell lines. more
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
GJA3
gap junction protein, alpha 3, 46kDa
total:1
Differential phosphorylation of connexin46 and connexin50 by H2O2 activation of protein kinase Cgamma. 2004 to the paper
Alpha Diagnostic Intl. Cx46 antibody was used in western blot and immunoprecipitation to determine how protein kinase Cgamma (PKCgamma) differentially regulates phosphorylation of Cx46 and Cx50 in oxidatively stressed lenses.
GJA8
gap junction protein, alpha 8, 50kDa
total:1
Differential phosphorylation of connexin46 and connexin50 by H2O2 activation of protein kinase Cgamma. 2004 to the paper
Zymed Laboratories Cx50 antibody was used in western blot and immunoprecipitation to determine how protein kinase Cgamma (PKCgamma) differentially regulates phosphorylation of Cx46 and Cx50 in oxidatively stressed lenses.
GJB1
gap junction protein, beta 1, 32kDa
total:4
Internalization of large double-membrane intercellular vesicles by a clathrin-dependent endocytic process. 2007 to the paper
Zymed Laboratories anti-Cx43 antibody was used in immunocytochemistry in order to investigate the mechanism of large, double-membrane vesicles internalization based on clathrin-dependent endocytosis. more
GJB2
gap junction protein, beta 2, 26kDa
total:6
Digenic inheritance of non-syndromic deafness caused by mutations at the gap junction proteins Cx26 and Cx31. 2009 to the paper
Zymed Laboratories anti-Cxs26 was used as primary antibody in immunoprecipitation in order to prove that the mutations at the two contributor genes of non-syndromic deafness can cause hearing loss in a heterozygous condition. more
GJB3
gap junction protein, beta 3, 31kDa
total:1
Digenic inheritance of non-syndromic deafness caused by mutations at the gap junction proteins Cx26 and Cx31. 2009 to the paper
Zymed Laboratories Anti-Cx31 was used to label the cryosections in order to prove that the mutations at the two contributor genes of non-syndromic deafness can cause hearing loss in a heterozygous condition.
GJB6
gap junction protein, beta 6, 30kDa
total:4
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
Invitrogen anti Cx301:5000 antibody was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
GJD4
gap junction protein, delta 4, 40.1kDa
GLUT4
solute carrier family 2 (facilitated glucose transporter), member 4
total:11
ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. 2009 to the paper
Millipore anti-Glut4 antibody was used to carry out western blot analysis in order to investigate the regulation of adipocyte glucose transport by ClipR-59 mediated Akt cellular compartmentalization. more
HCRP1
vacuolar protein sorting 37 homolog A (S. cerevisiae)
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
HIP1R
huntingtin interacting protein 1 related
Hsc70
heat shock 70kDa protein 8
total:25
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
Stressgen monoclonal anti-Hsc70 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
KIF3A
kinesin family member 3A
total:3
Kaposi's sarcoma-associated herpesvirus ORF45 interacts with kinesin-2 transporting viral capsid-tegument complexes along microtubules. 2009 to the paper
Sigma anti-KIF3A antibodies were used to perform immunofluorescence assays in order to demonstrate that KSHV tegument protein play a crucial role in cellular transport of viral particles. more
KIF3B
kinesin family member 3B
total:1
IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. 2003 to the paper
BD Biosciences mouse monoclonal KIF3B antibodies were used in immunoprecipitation to study the role of IFT proteins in the assembly and maintenance of eukaryotic cilia and flagella.
KIFAP3
kinesin-associated protein 3
total:3
Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2. 2008 to the paper
BD-Biosciences KAP3 antibody was used in western blot (1:500) to investigate the role of kinesin-2 in pVHL mobility. more
M6PR
mannose-6-phosphate receptor (cation dependent)
total:2
The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells. 2009 to the paper
Abcam polyclonal anti-mannose 6 phosphate receptor (M6PR) antibody was used in immunocytochemistry to study the effect of E693deletemutation in amyloid precursor protein on intracellular accumulation of amyloid beta oligomers and its role in causing endoplasmic reticulum stress-induced apoptosis in cultured cells more
MYH1
myosin, heavy chain 1, skeletal muscle, adult
total:7
C6ORF32 is upregulated during muscle cell differentiation and induces the formation of cellular filopodia. 2007 to the paper
DSHB anti-myosin heavy chain antibody was used to perform immunohistochemistry in order to study the roles of the C6ORF32 during the muscle cell differentiation and the formation of cellular filopodia. more
MYH13
myosin, heavy chain 13, skeletal muscle
total:2
Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles. 2003 to the paper
Developmental Studies Hybridoma Bank mouse monoclonal anti-MYH13 antibody (N.2.262) was used in immunohistochemistry to study its expression in human extraocular muscles more
MYH2
myosin, heavy chain 2, skeletal muscle, adult
total:3
Overexpression of the mitochondrial T3 receptor p43 induces a shift in skeletal muscle fiber types. 2008 to the paper
Alexis Biochemical monoclonal MyHC type IIa antibody was used in immunohistochemistry in order to examine the role of mitochondrial T3 receptor p43 in vivo muscle development and phenotype more
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
total:1
Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles. 2003 to the paper
Alan Kelly (University of Chicago, Chicago, IL) anti-MYH3 antibody (N.2.262) was used in immunohistochemistry to study its expression in human extraocular muscles
MYH4
myosin, heavy chain 4, skeletal muscle
total:2
Overexpression of the mitochondrial T3 receptor p43 induces a shift in skeletal muscle fiber types. 2008 to the paper
Alexis Biochemical monoclonal MyHC type IIb antibody was used in immunohistochemistry in order to examine the role of mitochondrial T3 receptor p43 in vivo muscle development and phenotype more
MYH7
myosin, heavy chain 7, cardiac muscle, beta
total:5
Overexpression of CUG triplet repeat-binding protein, CUGBP1, in mice inhibits myogenesis. 2004 to the paper
Sigma slow myosin heavy chain antibody was used in western blot to study the expression of the CUG triplet repeat-binding protein in myogenesis. more
MYH7B
myosin, heavy chain 7B, cardiac muscle, beta
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
MYO5A
myosin VA (heavy chain 12, myoxin)
total:1
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 to the paper
Sigma rabbit polyclonal anti-myosin V antibody was used to carry out western blot analysis in order to investigate the role for UNC-45 in the regulation of tumor cell proliferation and metastasis.
MYO6
myosin VI
total:2
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 to the paper
Sigma mouse anti-myosin VI antibody was used to carry out western blot analysis in order to investigate the role for UNC-45 in the regulation of tumor cell proliferation and metastasis. more
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
total:2
G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function. 2005 to the paper
Santa Cruz Biotechnology polyclonal anti-alphaSNAP antibody was used in immunocytochemistry to study the effects of interaction between G 12 and SNAP on VE-cadherin localization at endothelial junctions and barrier function. more
oxytocinase
leucyl/cystinyl aminopeptidase
total:4
Sensing of dietary lipids by enterocytes: a new role for SR-BI/CLA-1. 2009 to the paper
ABDSerotec sheep polyclonal anti-PLAP antibody (0300-1909) was used in western blot to analyze the early events that are specifically induced by the apical supply of PPM and to determine the molecular mechanisms of PPM sensing in enterocytes. more
PICALM
phosphatidylinositol binding clathrin assembly protein
total:5
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
BD Bioscience clathrin antibody was used to perform western blot in order to investigate internalization of ROR2 more
PIK3C2A
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
total:4
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
R&D technologies anti-PRKAA2 antibody was used to carry out western blot analysis and ChIP assays in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
total:2
Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite. 2003 to the paper
Upstate Biotechnology anti-AMPK beta2 antibody was used in western blot and immunoprecipitation to detect the interaction of AMPK and c-Src in the bovine aortic endothelial cells transfected with the adenoviral constructs for human SOD1, SOD2, and catalase. more
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
total:1
The ancient drug salicylate directly activates AMP-activated protein kinase. 2012 to the paper
Abcam anti-AMPK-gamma1 was used to perform western blot in order to show that AMPK could be activated by salicylate directly.
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
total:1
Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite. 2003 to the paper
Upstate Biotechnology anti-AMPK gamma2 antibody was used in western blot and immunoprecipitation to detect the interaction of AMPK and c-Src in the bovine aortic endothelial cells transfected with the adenoviral constructs for human SOD1, SOD2, and catalase.
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
total:1
Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite. 2003 to the paper
Upstate Biotechnology anti-AMPK gamma3 antibody was used in western blot and immunoprecipitation to detect the interaction of AMPK and c-Src in the bovine aortic endothelial cells transfected with the adenoviral constructs for human SOD1, SOD2, and catalase.
RAB4A
RAB4A, member RAS oncogene family
total:8
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-Rab4 antibody was used to perform western blot in order to investigate the mechanism for the long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. more
RAB5C
RAB5C, member RAS oncogene family
total:1
Ubiquitin binding and conjugation regulate the recruitment of Rabex-5 to early endosomes. 2008 to the paper
Santa Cruz Biotech rabbit Rab5c antibody was used in western blot in order to demonstrate that cycles of Ub binding and monoubiquitination regulate the association of Rabex-5 with endosomes.
Rab8
RAB8A, member RAS oncogene family
total:4
Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice. 2007 to the paper
BD Biosciences anti-Rab8 antibody was used to carry out immunofluorescence assays in order to investigate the role for Dlg5 in the maintenance of epithelial tube in mammalian brain and kidneys. more
RalA
v-ral simian leukemia viral oncogene homolog A (ras related)
total:6
Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation. 2006 to the paper
Santa Cruz Laboratories anti-Ral A antibody was used in western blot in order to investigate whether the signals generated by Ras proteins were affected by microlocalization and its important biological outcomes. more
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
RPS27A
ribosomal protein S27a
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
SAR1B
secretion associated, Ras related GTPase 1B
SEC23A
Sec23 homolog A (S. cerevisiae)
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents Sec23 antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
SH3GL2
SH3-domain GRB2-like 2
total:1
Study of the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma. 2007 to the paper
Santa Cruze SH3GL2 goat polyclonal antibody was used in western blot to study the SH3-study the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma.
SNAP23
synaptosomal-associated protein, 23kDa
total:2
A role for VAMP8/endobrevin in surface deployment of the water channel aquaporin 2. 2010 to the paper
Synaptic Systems rabbit anti-SNAP23 antibody was used for western blot in order to investigate the role of VAMP8/Endobrevin in the regulation of the surface deployment of the water channel AQP2. more
SNF8
SNF8, ESCRT-II complex subunit
total:1
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. 2007 to the paper
Eurogenetec rabbit Vps22 antibody was used in western blot in order to demonstrate that efficient autophagic degradation of protein aggregates associated with neurodegenerative disease requires functional multivesicular bodies (MVBs).
SNX2
sorting nexin 2
total:3
A role for EHD4 in the regulation of early endosomal transport. 2008 to the paper
Transduction Laboratories mouse monoclonal anti-SNX2 antibody was used to carry out immunofluorescence assays in order to investigate the role for EHD4 in the control of trafficking at the early endosome. more
SNX5
sorting nexin 5
total:1
A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer. 2007 to the paper
Santa Cruz goat polyclonal anti-SNX5 antibody was used in western blot and immunoprecipitation to study SNX5 and SNX6 as potential components of the mammalian retromer through a loss-of-function screen
SORT1
sortilin 1
total:3
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. 2005 to the paper
BD Biosciences anti-sortilin antibody was used in western blot and immunocytochemistry to study the role of sortilin in brain-derived neurotrophic factor secretory pathway more
Src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
total:1
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
ProteinTech Group STAM-1 polyclonal antibody was used to perform western blot and immunoprecipitation in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS.
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
stratifin
total:6
Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ labeling, multidimensional liquid chromatography, and tandem mass spectrometry. 2008 to the paper
Santa Cruz Biotechnology anti-stratifin antibody was used in immunohistochemistry and western blot to discover head-and-neck cancer biomarkers. more
STX4
syntaxin 4
total:5
A role for VAMP8/endobrevin in surface deployment of the water channel aquaporin 2. 2010 to the paper
Synaptic Systems rabbit anti-syntaxin 4 antibody was used for western blot in order to investigate the role of VAMP8/Endobrevin in the regulation of the surface deployment of the water channel AQP2. more
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D4
TBC1 domain family, member 4
total:2
ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. 2009 to the paper
Millipore anti-AS160 antibody was used to carry out western blot analysis in order to investigate the regulation of adipocyte glucose transport by ClipR-59 mediated Akt cellular compartmentalization. more
TBC1D8B
TBC1 domain family, member 8B (with GRAM domain)
TGN46
trans-golgi network protein 2
total:22
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
AbD Serotec anti-TGN46 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
transferrin receptor
total:70
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-CD71-APC antibody was used to perform flow cytometry in order to study the different trafficking mechanisms of endosomal Toll-like receptors mediated by UNC93B1. more
TSG101
tumor susceptibility 101
total:15
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Abcam monoclonal anti-Tsg101 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
UBA52
ubiquitin A-52 residue ribosomal protein fusion product 1
total:22
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region. 2004 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot to study the interaction of Fbx7 with Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) in the SCF complex. more
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
ubiquitin
ubiquitin B
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
total:8
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-synaptobrevin-2 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
VAMP7
vesicle-associated membrane protein 7
total:2
A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels. 2009 to the paper
Abcam VAMP7 antibody was used in immunocytochemistry in order to investigate the role of SNARE complex containing VAMP7 and Vti1a in the regulation of a novel traffic pathway to the cell surface in both neuronal and non-neuronal cells. more
VAMP8
vesicle-associated membrane protein 8
total:1
Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion. 2002 to the paper
Abcam anti-VAMP-8 was used in western blot to detect the presence of VAMP-8 in human platelets.
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
total:1
YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42. 2006 to the paper
Santa Cruz Biotechnology anti-VPS28 antibody was used in western blot to study YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42.
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS37C
vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-SKD1 antibody was used in western blot to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
total:1
YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42. 2006 to the paper
Santa Cruz Biotechnology anti-VPS4B amino terminus antibody was used in western blot to study YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42.
VTA1
vesicle (multivesicular body) trafficking 1
ZO 1
tight junction protein 1
total:55
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Zymed mouse anti-ZO-1 (1:1,000) antibody was used to perform immunofluorescence in order to study the role for TRAF4, a novel phosphoinositide-binding protein, in modulating tight junctions and favoring cell migration. more