Membrane Trafficking
gene
reagent
sample publication
sample review
total:3
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1g antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
V. Faundez anti-sigma3-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
total:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 to the paper
BD Biosciences monoclonal anti-AP50 antibody was used in human HeLa cells or HUVECs and in western blot to study the role for clathrin adaptor AP2 in regulating thrombin receptor constitutive internalization and endothelial cell resensitization. more
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
V. Faundez anti-deta3-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
total:1
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti- AP4e antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis.
total:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 to the paper
Affinity Bioreagents anti-Arf antibody was used to perform western blot in order to study the interaction between Arf and Poliovirus Protein 3CD and its effect on poliovirus replication. more
total:7
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
Santa Cruz Biotechnology beta-arrestin1/2 rabbit polyclonal antibody (21-B1) was used to perform western blot in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS. more
total:16
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents beta-COP antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
total:1
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. 2011 to the paper
Abcam antibody mouse rabbit anti-CHMP2B antibody was used to perform immunohistochemistry in order to study
quantification of CHMP2B on intercellular bridges at different stages.
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-Vps24 antibody was used in western blot to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-Snf7-1 antibody was used in western blot and immunocytochemistry to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
total:1
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. 2011 to the paper
Santa Cruz antibody anti-CHMP4B antibody was used to perform immunohistochemistry in order to study
quantification of CHMP4B on intercellular bridges at different stages.
total:8
Vaccinia virus p37 interacts with host proteins associated with LE-derived transport vesicle biogenesis. 2009 to the paper
Affinity BioReagents CI-MPR was used as primary antibody in immunofluorecent staining in order to study the interaction between the vaccinia virus p37 and host proteins associated with LE-derived transport vesicle biogenesis. more
total:27
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
BD Transduction Labs anti-clathrin heavy chain antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
total:5
Regulation of myosin-VI targeting to endocytic compartments. 2004 to the paper
BD Transduction Laboratories anti-clathrin antibody was used in immunocytochemistry to study the role for splicing in the recruitment of myo6 to distinct endocytic compartments in human ARPE-19 cells. more
total:2
Association of the Hermansky-Pudlak syndrome type-3 protein with clathrin. 2005 to the paper
BD Biosciences Pharmingen mouse monoclonal anti-clathrin heavy chain antibody was used in western blot and immunocytochemistry to study the association of the Hermansky-Pudlak syndrome type-3 protein with clathrin. more
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents alpha-COP antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
total:6
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 to the paper
Novus Biologicals anti- beta-COP antibody was used in immunocytochemistry in order to investigate the mechanism of an autonomous cholesterol regulation activated by adenovirus membrane protein RID-alpha. more
total:1
Transport of the IgE receptor alpha-chain is controlled by a multicomponent intracellular retention signal. 2006 to the paper
Santa Cruz Biotechnology anti-gamma-COPI antibody (sc-14167) was used in human HEK293 cells and in western blot to study the role of the multicomponent intracellular retention signal in controlling transport of the IgE receptor alpha-chain.
total:1
Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair. 2007 to the paper
MBL International mouse anti-CPD was used to perform western blot in order to investigate the role of XPC protein in the initiation of nucleotide excision repair.
total:20
CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus. 2009 to the paper
Santa Cruz Biotech polyclonal goat anti-connexin 43 antibody was used in immunohistochemistry in order to demonstrate that the normal human cornea is equipped with a molecular tool to actively metabolize NAD+, helping maintain corneal homeostasis more
total:10
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension. 2011 to the paper
Santa Cruz antibody polyclonalanti-Dab2 antibody was used to perform immunohistochemistry in order to study the expression of KCNJ5 in adrenal glomerulosa. more
total:6
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells. 2007 to the paper
BD Biosciences anti-dynamin-2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism of entry for Chlamydia trachomatis into nonphagocytic cells. more
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
E. Dell'Angelica anti-Dysbindin in antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
total:15
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Santa Cruz Biotechnology monoclonal anti-dynamin 1 antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
total:6
PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element. 2007 to the paper
Santa Cruz Biotechnology anti-ferritin H antibody was used to perform western blot in order to investigate the role of PIAS3 in the ARE-mediated transcription of the ferritin H gene. more
total:4
Control of iron homeostasis by an iron-regulated ubiquitin ligase. 2009 to the paper
Sigma anti-ferritin antibody was used to perform western blot in order to study the roles of the iron-regulated ubiquitin ligase in the regulation towards the iron homeostasis.
more
total:1
The DnaJ-domain protein RME-8 functions in endosomal trafficking. 2005 to the paper
MBL International mouse monoclonal antibody against auxilin 2 (also known as cyclin-G-associated kinase) was used in western blot to study the function of a DnaJ domain-containing protein RME-8 in endosomal trafficking.
total:15
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins. 2007 to the paper
BD Biosciences monoclonal clathrin heavy chain antibody was used in immunocytochemistry to study the role of syntaxin 16 and syntaxin 5 in efficient retrograde transport of several exogenous and endogenous cargo proteins more
total:1
Differential phosphorylation of connexin46 and connexin50 by H2O2 activation of protein kinase Cgamma. 2004 to the paper
Alpha Diagnostic Intl. Cx46 antibody was used in western blot and immunoprecipitation to determine how protein kinase Cgamma (PKCgamma) differentially regulates phosphorylation of Cx46 and Cx50 in oxidatively stressed lenses.
total:1
Differential phosphorylation of connexin46 and connexin50 by H2O2 activation of protein kinase Cgamma. 2004 to the paper
Zymed Laboratories Cx50 antibody was used in western blot and immunoprecipitation to determine how protein kinase Cgamma (PKCgamma) differentially regulates phosphorylation of Cx46 and Cx50 in oxidatively stressed lenses.
total:5
Internalization of large double-membrane intercellular vesicles by a clathrin-dependent endocytic process. 2007 to the paper
Zymed Laboratories anti-Cx43 antibody was used in immunocytochemistry in order to investigate the mechanism of large, double-membrane vesicles internalization based on clathrin-dependent endocytosis. more
total:6
Digenic inheritance of non-syndromic deafness caused by mutations at the gap junction proteins Cx26 and Cx31. 2009 to the paper
Zymed Laboratories anti-Cxs26 was used as primary antibody in immunoprecipitation in order to prove that the mutations at the two contributor genes of non-syndromic deafness can cause hearing loss in a heterozygous condition. more
total:1
Digenic inheritance of non-syndromic deafness caused by mutations at the gap junction proteins Cx26 and Cx31. 2009 to the paper
Zymed Laboratories Anti-Cx31 was used to label the cryosections in order to prove that the mutations at the two contributor genes of non-syndromic deafness can cause hearing loss in a heterozygous condition.
total:4
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
Invitrogen anti Cx301:5000 antibody was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
total:25
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-Hsc70 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:2
The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells. 2009 to the paper
Abcam polyclonal anti-mannose 6 phosphate receptor (M6PR) antibody was used in immunocytochemistry to study the effect of E693deletemutation in amyloid precursor protein on intracellular accumulation of amyloid beta oligomers and its role in causing endoplasmic reticulum stress-induced apoptosis in cultured cells more
total:3
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 to the paper
Sigma mouse anti-myosin VI antibody was used to carry out western blot analysis in order to investigate the role for UNC-45 in the regulation of tumor cell proliferation and metastasis. more
total:2
G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function. 2005 to the paper
Santa Cruz Biotechnology polyclonal anti-alphaSNAP antibody was used in immunocytochemistry to study the effects of interaction between G 12 and SNAP on VE-cadherin localization at endothelial junctions and barrier function. more
total:5
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
BD Bioscience clathrin antibody was used to perform western blot in order to investigate internalization of ROR2 more
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
E. Dell'Angelica anti-Pallidin in antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
total:1
Ubiquitin binding and conjugation regulate the recruitment of Rabex-5 to early endosomes. 2008 to the paper
Santa Cruz Biotech rabbit Rab5c antibody was used in western blot in order to demonstrate that cycles of Ub binding and monoubiquitination regulate the association of Rabex-5 with endosomes.
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents Sec23 antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
total:1
Study of the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma. 2007 to the paper
Santa Cruze SH3GL2 goat polyclonal antibody was used in western blot to study the SH3-study the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma.
total:2
A role for VAMP8/endobrevin in surface deployment of the water channel aquaporin 2. 2010 to the paper
Synaptic Systems rabbit anti-SNAP23 antibody was used for western blot in order to investigate the role of VAMP8/Endobrevin in the regulation of the surface deployment of the water channel AQP2. more
total:1
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. 2007 to the paper
Eurogenetec rabbit Vps22 antibody was used in western blot in order to demonstrate that efficient autophagic degradation of protein aggregates associated with neurodegenerative disease requires functional multivesicular bodies (MVBs).
total:3
A role for EHD4 in the regulation of early endosomal transport. 2008 to the paper
Transduction Laboratories mouse monoclonal anti-SNX2 antibody was used to carry out immunofluorescence assays in order to investigate the role for EHD4 in the control of trafficking at the early endosome. more
total:1
A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer. 2007 to the paper
Santa Cruz goat polyclonal anti-SNX5 antibody was used in western blot and immunoprecipitation to study SNX5 and SNX6 as potential components of the mammalian retromer through a loss-of-function screen
total:3
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. 2005 to the paper
BD Biosciences anti-sortilin antibody was used in western blot and immunocytochemistry to study the role of sortilin in brain-derived neurotrophic factor secretory pathway more
total:116
miR-126 regulates angiogenic signaling and vascular integrity. 2008 to the paper
Cell Signaling anti-SRC and phospho-SRC (Tyr416) was used to perform western blot in order to show that vascular integrity and angiogenesis are regulated by miR-126. more
total:1
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
ProteinTech Group STAM-1 polyclonal antibody was used to perform western blot and immunoprecipitation in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS.
total:5
A role for VAMP8/endobrevin in surface deployment of the water channel aquaporin 2. 2010 to the paper
Synaptic Systems rabbit anti-syntaxin 4 antibody was used for western blot in order to investigate the role of VAMP8/Endobrevin in the regulation of the surface deployment of the water channel AQP2. more
total:22
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
AbD Serotec anti-TGN46 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and
anabolic machinery in facilitating the synthesis of secretory proteins. more
total:68
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Beckman-coulter APC-conjugated anti-CD71 was used to perform flow cytometry in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:14
Essential role of hIST1 in cytokinesis. 2009 to the paper
Abcam anti-TSG101 antibody was used to perform western blot in order to show that the hIST1 play an important role in cytokinesis. more
total:22
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region. 2004 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot to study the interaction of Fbx7 with Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) in the SCF complex. more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:4
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. 2007 to the paper
Dako anti-ubiquitin antibody was used in immunohistochemistry to study whether PGRN genetic variability contributed to other common neurodegenerative brain diseases, such as Alzheimer disease (AD) or Parkinson disease (PD) in sections from human. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:8
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-synaptobrevin-2 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:3
A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels. 2009 to the paper
Abcam VAMP7 antibody was used in immunocytochemistry in order to investigate the role of SNARE complex containing VAMP7 and Vti1a in the regulation of a novel traffic pathway to the cell surface in both neuronal and non-neuronal cells. more
total:1
Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion. 2002 to the paper
Abcam anti-VAMP-8 was used in western blot to detect the presence of VAMP-8 in human platelets.
total:1
YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42. 2006 to the paper
Santa Cruz Biotechnology anti-VPS28 antibody was used in western blot to study YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42.
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-SKD1 antibody was used in western blot to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
total:1
YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42. 2006 to the paper
Santa Cruz Biotechnology anti-VPS4B amino terminus antibody was used in western blot to study YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42.
total:53
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
Invitrogen anti-ZO-1 antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more